Cathartics and laxatives increase the motility of the intestine or increase the bulk of feces. different types of contrast X-rays, CTs, MRIs). Concomitant illnesses may make it more difficult for the treating physician to determine the diagnosis or treatment of the primary illness. If the blocked drug remains in its active form, symptoms of an overdose of that medication may develop, despite the patient having taken the drugs exactly as ordered. Examples of concomitant in a sentence, how to use it. Intervention: Monitor for adverse reactions and reduce dosage of Paxil CR or other protein-bound drugs as warranted. Choose the design that fits your site.  |  Most English definitions are provided by WordNet . This designation is used when 2 or more medicinal drugs are given either at the same time, or almost at the same time, for instance one after the other, or on the same day, etc. Remember to tell any doctor or dentist about your MG diagnosis. The Number of Concomitant Drugs and the Safety of Direct Oral Anticoagulants in Routine Care Patients with Atrial Fibrillation. Concomitant drugs . We recruited 1,170 patients (mean age 60.1 years, 56.4% male). The concomitant use of Zoloft with another drug that is highly bound to plasma protein may increase free concentrations of Zoloft or other tightly-bound drugs in plasma. Concomitant drugs Definition from Encyclopedia Dictionaries & Glossaries. The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. With a SensagentBox, visitors to your site can access reliable information on over 5 million pages provided by Sensagent.com. The common examples are Headache > by profuse urination of Gelsemium, Coryza associated with polyurea of Cal carb, Pain with chilliness of puls, Prolapse and uterine affection which is > ted by crossing legs but with empty all gone sinking feeling in abdomen and less sexual desire of Sepia etc. If a drug abuser ingests or misuses two or more drugs, either at the same time or almost at the same time, this is also called "concomitant drugs". For this reason, doctors often ask patients what medications they are regularly taking with every office appointment, and pharmacists carefully monitor patients’ drug regimes. Tips: browse the semantic fields (see From ideas to words) in two languages to learn more. The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. Certain medications and over the counter preparations may cause worsening of MG symptoms. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Often, they monitor the kidney function and the hydration status of their patients during the imaging procedure, especially whenever a concomitant drug (that is harmful to the kidney) is being used.[2]. You can feel safe while using our website. The designation concomitant drugs has two contextual uses: as used in medicine or as used in drug abuse. Wikipedia Dictionaries. Intervention: Monitor for adverse reactions and reduce dosage of Zoloft or other protein-bound drugs as warranted. The influence of concomitant medications on hepatic and intestinal metabolism becomes more complicated when a drug, including a prodrug, is metabolized to one or more active metabolites. Examples thereof include excipients, lubricants, binders and disintegrators for solid preparations; and solvents, solubilizing aids, suspending agents, isotonic agents, buffers and soothing agents for liquid preparations. Your personal information will stay completely confidential and will not be disclosed to any third party. However, if you don’t like your paper for some reason, you can always receive a refund. If a patient is taking a medication PRN, do not use a separate line for each time the medication is taken, instead report the first and last dates taken. These are imaging procedures in medicine that are performed after giving the patient an iodinated contrast medium (e.g. ○   Anagrams Concomitant drug therapy may alter insulin requirements. Give contextual explanation and translation from your sites ! See if you can get into the grid Hall of Fame ! Indication concomitant definition: 1. something that happens with something else and is connected with it: 2. happening and connected…. Examples: warfarin: Drugs Metabolized by CYP2D6 In addition to producing side effects when combined, concomitant drugs can also block or slow another drug’s metabolism by interfering with the digestive pathway or excretion by the kidneys or the liver, thereby markedly increasing the blocked drug’s half-life. Use of other drugs in combination with psychostimulants may influence either the acute effects of either drug, or the longer-term risks associated with psychostimulant use. Over time, this information can reveal combined side effects from concomitant drugs. 100 examples: Disorganized attachment in early childhood : meta-analysis of precursors… Boggle gives you 3 minutes to find as many words (3 letters or more) as you can in a grid of 16 letters. An integral aspect of the information they continue to collect is the other drugs a patient takes in addition to their own medication. Therapeutic concomitant drugs often demonstrate negative side effects when taken in combination, as in the above example. However, there are concerns that the rate of concomitant use of gastroprotective drugs in elderly NSAID users is too low. The treatment of these other diseases has an effect on blood sugar levels, so the patient's usual diabetes treatment may have to be changed. Concomitant drugs refer to two or more drugs or medications taken at the same time. ), http://www.bccancer.bc.ca/HPI/ChemotherapyProtocols/default.htm. Concomitant drugs in medicine. the risk damage to the kidneys). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If the patient is receiving a "concomitant" medicinal drug (prescribed to the patient by another physician), and the radiologist performing the imaging procedure is unaware of this, potentially harmful side-effects can occur and increase the risk of contrast medium-induced nephropathy (i.e. Concomitant use of drugs affecting the renin-angiotensin system Combination therapy with two drugs affecting the renin-angiotensin system (ACE inhibitors, angiotensin-II receptor antagonists, and aliskiren is not recommended due to an increased risk of hyperkalaemia, hypotension, and renal impairment, compared to use of a single drug. United States Patent Application 20050197376 .  | Last modifications, Copyright © 2012 sensagent Corporation: Online Encyclopedia, Thesaurus, Dictionary definitions and more. Examples of drug-specific factors include their cytotoxic effect on cells, mechanisms of clearance, and concomitant use with other non-chemotherapeutic nephrotoxic agents. Cautionary Drugs. Ethanol Nicotine ... Concomitant marijuana use may increase the pharmacologic and toxic effects of cocaine. Moons,1Arno W. Hoes,1Geert-Jan Geersing,1and Hendrika A. van den Ham2. We do our best to make our customers satisfied with the result. According to the NIDA, As the name suggests, stimulants increase alertness, attention, and energy, as well as elevate blood pressure, heart rate, and respiration. Confidentiality Guaranteed Get XML access to reach the best products. Carline J. van den Dries. Stimulants are a class of drugs that all cause similar effects on the body and mind. Find out more, an offensive content(racist, pornographic, injurious, etc. Alternately, a blocked drug may remain unable to reach its potent active metabolite and prove ineffective for the patient at a therapeutically prescribed and administered dosage. It is recommended that gastroprotective drugs (i.e. The concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven. This is often the case in medicine. They may also can lead to kidney damage. Concomitant drugs are two or more drugs used or given at or almost at the same time (one after the other, on the same day, etc.). Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDS), other antiplatelet drugs, warfarin, and other anticoagulants may add to this risk. Concomitant drugs refer to two or more drugs or medications taken at the same time. ○   Lettris First example. It is important to check with your doctor before starting any new medication including over the counter medications or preparations. Descriptive statistical analysis. Conversely, street and recreational drugs are also often combined in opposition to the primary effect of each — so as to minimize the unpleasant or undesired side effects — such as the concomitant use of cocaine and alcohol. Table 3-2: Examples of clinical inhibitors for P450-mediated metabolisms (for concomitant use clinical DDI studies and/or drug labeling) (03/06/2020) Strong inhibitors Moderate inhibitors Privacy policy Record all concomitant medications, including therapies given to treat adverse events. Drugs that may decrease insulin requirements include alcohol, anabolic steroids, aspirin, fenfluramine and monoamine oxidase inhibitors; there have been isolated reports of decreased insulin requirements with captopril, clofibrate, cyclophosphamide, guanethidine, mebendazole, methandienone and oxytetracycline. The web service Alexandria is granted from Memodata for the Ebay search. Concomitant definition: Concomitant is used to describe something that happens at the same time as another thing... | Meaning, pronunciation, translations and examples misoprostol, proton pump inhibitors or high doses of histamine H2 receptor antagonists) be taken concomitantly to prevent NSAID-induced GI complications among older people. an opiate plus another drug of misuse) leads to an increased number of acute accidental opiate-related deaths. Examples: warfarin: Drugs Metabolized by CYP2D6: Clinical Impact: Each square carries a letter. It is well known that such iodinated contrast media can lead to acute allergies in some patients. Concomitant medication is combining two or more treatment regimes when treating diseases. These 2 chemotherapy protocols are very similar in principle. The wordgames anagrams, crossword, Lettris and Boggle are provided by Memodata. How to use concomitant in a sentence. You can make sure yourself by using our Plagiarism Check service, This site is protected by wp-copyrightpro.com. For instance, chemotherapy is often cited as a prime example of therapeutic concomitant drugs wher… The most common drug combined with others in this type of concomitant drug abuse is alcohol. Ro, Cookies help us deliver our services. For instance, chemotherapy is often cited as a prime example of therapeutic concomitant drugs whereby two or more medications are administered literally at the same time for the sake of the patient’s health. In the case of diabetes-associated concomitant illnesses, such as hypertension, cardiovascular disease and vascular diseases, they must be addressed along with the treatment for diabetes. The standard of care (sometimes also called the "gold standard") for the adjuvant treatment of stage III colon cancer is the FOLFOX chemotherapy protocol (used in Europe, Japan, Canada, and Australia) and respectively the FLOX chemotherapy protocol (used in the USA). Carline J. van den Dries,1Sander van Doorn,1Patrick Souverein,2Romin Pajouheshnia,2Karel G.M. A windows (pop-into) of information (full-content of Sensagent) triggered by double-clicking any word on your webpage. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 … This designation is used when 2 or more medicinal drugs are given either at the same time, or almost at the same time, for instance one after the other, or on the same day, etc. The percentages of potential / possible DI between the DAAs and the concomitant drugs on the CNS were: 2.7% … The term has two contextual uses: as used in medicine or as used in drug abuse. Chemotherapy for cancer applies as an example. Contact Us Pharmaceutical companies continue to collect data on reported side effects of the medications they manufacture long after approval testing is complete. None Medication . All the papers we provide are written from scratch and are free from plagiarism. Whether concomitant drug abuse leads to an increased number of deaths was scientifically analysed in Sheffield, UK. English thesaurus is mainly derived from The Integral Dictionary (TID). Letters must be adjacent and longer words score better. Concomitant drugs refer to two or more drugs or medications taken at the same time. Concomitant drugs: lt;p|>|Concomitant drugs| are two or more |drugs| used or given at or almost at the same time (on... World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, and the most definitive collection ever assembled. Get XML access to fix the meaning of your metadata.  |  You can also try the grid of 16 letters. ○   Boggle. By using our services, you agree to our use of cookies. Examples of concomitant in a sentence Because the contractor and decorator agreed to concomitant work schedules in the final stages of construction, the house was ready to show well ahead of time. The concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven. Ho… Did You Know? Purpose. Mean concomitant drug use was 3.2 per patient/year. The authors showed that at least in the Sheffield area, intravenous (IV) administration of an opiate is the most consistent factor associated with drug abuse deaths. If a drug abuser ingests or misuses two or more drugs, either at the same time, or almost at the same time, for instance one after the other, or on the same day, etc, this is also called "concomitant drugs". English Wikipedia - The Free Encyclopedia. Yet, another example of concomitant drugs could be tetracycline antibiotics taken with supplemental calcium, where the calcium is taken just once in the morning and the antibiotic is administered every 6 hours until completed. All rights reserved. ○   Wildcard, crossword At end of study only: Check this box if participant took no concomitant medication . Concomitant use of clinical status; occurrence suspected, established nonsteroidal antiinflammatory drugs (NSAIDs) with or probable in well-controlled studies 3 Interaction causes minor effects; occurrence warfarin is one of the examples for pharmacodynamic suspected, established or probable in interaction. Change the target language to find translations. These substances can be beneficial in many ways and may be used to help individuals with learning or mental disorders become more focused and lead more productive lives. Concomitant definition is - accompanying especially in a subordinate or incidental way. The English word games are: Learn more. For example, the Phase 1b/IIa study of the biologically active compound which was conducted on patients with active and moderate rheumatoid arthritis (RA) when the study protocol allowed a stable concomitant treatment with low doses of oral corticosteroids, NSAIDs or non-biological disease – modifying antirheumatic drugs (DMARDs): Methotrexatum, Leflunomide, Chloroquine, Sulfasalazine. Ad This type of concomitant use can be used to potentiate the desired effect of the medications, such as in the use of tranquilizers with sedatives. The co-administration of a concomitant drug of misuse appeared to be a feature rather than a risk factor per se in such deaths.[3]. Kind Code: A1 . Graphical extrapolations of historical prevalence of FGM have shown a shift in the practice by gradual decline in infibulations and concomitant rise in clitoridectomies. Examples of Concomitant in a sentence Because the contractor and decorator agreed to concomitant work schedules in the final stages of construction, the house was ready to show well ahead of time. To make squares disappear and save space for other squares you have to assemble English words (left, right, up, down) from the falling squares. Company Information This is often the case in medicine. The concomitant use of Paxil CR with another drug that is highly bound to plasma protein may increase free concentrations of Paxil CR or other tightly-bound drugs in plasma. Both consist of 3 medicinal drugs: a) Leucovorin (= folinic acid = calcium folinate), b) 5-Fluorouracil (= 5-FU), and c) Oxaliplatin. Since these 3 medicinal drugs are "concomitant" to each other, such a constellation is called "concomitant drugs". Lettris is a curious tetris-clone game where all the bricks have the same square shape but different content. English Encyclopedia is licensed by Wikipedia (GNU). The Concomitant Medications module was one of the group of variables included in the third round of the CRF Harmonization and Standardization Initiative. In addition showing how in this case, “the same time” means “same day,” this example illustrates one of the negative effects of drugs taken concomitantly — side effects that occur in combination — as concomitant calcium use decreases the effectiveness of the antibiotics. Add new content to your site from Sensagent by XML. Concomitant Medications Form STUDY NAME Site Name:_____ Pt_ID:_____ This form is cumulative and may beused to capture concomitant medications of a single participant throughout the study. Concomitant Medications NCI CRF Standards: Round 3. The authors wanted to find out whether concomitant drug abuse (i.e. In general, radiologists carefully ask their patients about other medicinal drugs they are "concomitantly" taking before the imaging procedure. [1], Contrast imaging in medicine is another example. Chemotherapy for cancer applies as an example. Concomitant drugs is also a term recognized with drug abuse or recreational use of street drugs. Cannabis levels seem to be unaffected by cocaine. The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. The SensagentBox are offered by sensAgent.